Chef Sofia

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July 29, 2025
Ultimate Comfort: Mac and Cheese Meatloaf Casserole Magic - Featured Image

There’s something incredibly comforting about a dish that combines two beloved classics into one. Today, I’m excited to share a recipe that’s close to my heart: Mac and Cheese Meatloaf Casserole. Growing up in a lively Mexican-American household, our meals were always about bringing people together, sharing stories, and savoring each bite. This dish embodies that spirit, combining the warmth of meatloaf with the creamy delight of mac and cheese. It’s a meal that feels like a hug on a plate, and I’m thrilled to guide you through making it.

Why You’ll Love This Mac and Cheese Meatloaf Casserole

What makes the Mac and Cheese Meatloaf Casserole so special is its ability to bring together the heartiness of meatloaf with the gooey, cheesy comfort of mac and cheese. It’s a dish that’s perfect for family gatherings or a cozy dinner at home. My grandmother always believed that food was meant to be shared and enjoyed with those you love, and this casserole is a testament to that philosophy. It’s simple enough for a weeknight dinner but special enough to serve when you have guests over. Plus, it’s a fantastic way to introduce some creativity into your cooking, transforming two traditional dishes into one unforgettable meal.

Ingredients You’ll Need for This Mac and Cheese Meatloaf Casserole

Ingredients for Ultimate Comfort: Mac and Cheese Meatloaf Casserole Magic

To create this delicious casserole, you’ll need the following ingredients:

  • 1 lb ground beef
  • 1 lb ground pork
  • 1 cup breadcrumbs
  • 1/2 cup milk
  • 1 large egg
  • 1 small onion, finely chopped
  • 2 cloves garlic, minced
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 2 cups elbow macaroni
  • 2 cups shredded cheddar cheese
  • 2 cups milk
  • 2 tablespoons butter
  • 2 tablespoons all-purpose flour
  • 1/2 teaspoon mustard powder
  • Salt and pepper to taste

If you’re looking to make this dish a bit lighter, you can substitute ground turkey for the beef and pork. For a gluten-free version, use gluten-free breadcrumbs and pasta. Flexibility is key, just as my grandmother taught me when we would cook together, adjusting recipes based on what we had on hand.

Nutrition Facts

Here’s a breakdown of the nutrition facts for this comforting casserole:

  • Calories: 550 per serving
  • Protein: 30g
  • Fat: 35g
  • Carbohydrates: 32g
  • Fiber: 2g
  • Sugar: 5g
  • Sodium: 800mg

These values are based on a generous serving size, perfect for those evenings when you need a little extra comfort. Remember, part of the joy of cooking is sharing, so feel free to adjust portion sizes to suit your needs.

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Ultimate Comfort: Mac and Cheese Meatloaf Casserole Magic - Featured Image

Ultimate Comfort: Mac and Cheese Meatloaf Casserole Magic

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Learn how to make delicious Mac and Cheese Meatloaf Casserole. Easy recipe with step-by-step instructions.

  • Total Time: 45 minutes
  • Yield: 4 servings

Ingredients

To create this delicious casserole, you’ll need the following ingredients:

  • 1 lb ground beef
  • 1 lb ground pork
  • 1 cup breadcrumbs
  • 1/2 cup milk
  • 1 large egg
  • 1 small onion, finely chopped
  • 2 cloves garlic, minced
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 2 cups elbow macaroni
  • 2 cups shredded cheddar cheese
  • 2 cups milk
  • 2 tablespoons butter
  • 2 tablespoons all-purpose flour
  • 1/2 teaspoon mustard powder
  • Salt and pepper to taste

If you’re looking to make this dish a bit lighter, you can substitute ground turkey for the beef and pork. For a gluten-free version, use gluten-free breadcrumbs and pasta. Flexibility is key, just as my grandmother taught me when we would cook together, adjusting recipes based on what we had on hand.

Instructions

  1. Preheat your oven to 350°F. Grease a 9×13 inch baking dish and set it aside.
  2. In a large bowl, combine the ground beef, ground pork, breadcrumbs, 1/2 cup milk, egg, onion, garlic, Worcestershire sauce, 1 teaspoon salt, and 1/2 teaspoon black pepper. Mix until well combined.
  3. Press the meat mixture into the prepared baking dish, forming an even layer. Bake for 25 minutes.
  4. While the meatloaf is baking, cook the elbow macaroni according to package instructions until al dente. Drain and set aside.
  5. In a saucepan over medium heat, melt the butter. Stir in the flour and mustard powder, cooking for 1-2 minutes until golden.
  6. Slowly whisk in the 2 cups of milk, bringing the mixture to a simmer. Cook until it thickens slightly, about 5 minutes.
  7. Remove from heat and stir in the shredded cheddar cheese until melted and smooth. Season with salt and pepper to taste.
  8. Combine the cooked macaroni with the cheese sauce, mixing well.
  9. Once the meatloaf has baked for 25 minutes, remove it from the oven and spread the mac and cheese evenly over the top.
  10. Return the dish to the oven and bake for an additional 15 minutes, or until the cheese is bubbling and golden.
  11. Let the casserole rest for 5 minutes before serving, allowing the flavors to meld together beautifully.

Cooking this dish reminds me of the times I’d help my abuela in the kitchen, learning to trust my senses and adjust spices to taste. Feel free to do the same as you prepare this dish!

  • Author: Jenny
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Dish
  • Method: Cooking
  • Cuisine: International

Steps to Create Your Mac and Cheese Meatloaf Casserole

  1. Preheat your oven to 350°F. Grease a 9×13 inch baking dish and set it aside.
  2. In a large bowl, combine the ground beef, ground pork, breadcrumbs, 1/2 cup milk, egg, onion, garlic, Worcestershire sauce, 1 teaspoon salt, and 1/2 teaspoon black pepper. Mix until well combined.
  3. Press the meat mixture into the prepared baking dish, forming an even layer. Bake for 25 minutes.
  4. While the meatloaf is baking, cook the elbow macaroni according to package instructions until al dente. Drain and set aside.
  5. In a saucepan over medium heat, melt the butter. Stir in the flour and mustard powder, cooking for 1-2 minutes until golden.
  6. Slowly whisk in the 2 cups of milk, bringing the mixture to a simmer. Cook until it thickens slightly, about 5 minutes.
  7. Remove from heat and stir in the shredded cheddar cheese until melted and smooth. Season with salt and pepper to taste.
  8. Combine the cooked macaroni with the cheese sauce, mixing well.
  9. Once the meatloaf has baked for 25 minutes, remove it from the oven and spread the mac and cheese evenly over the top.
  10. Return the dish to the oven and bake for an additional 15 minutes, or until the cheese is bubbling and golden.
  11. Let the casserole rest for 5 minutes before serving, allowing the flavors to meld together beautifully.

Cooking this dish reminds me of the times I’d help my abuela in the kitchen, learning to trust my senses and adjust spices to taste. Feel free to do the same as you prepare this dish!

Tips for Making the Best Mac and Cheese Meatloaf Casserole

To make this casserole even more delightful, here are some tips straight from my kitchen to yours:

  • Cheese Choices: Feel free to experiment with different cheeses. A mix of sharp cheddar and Monterey Jack can add an extra layer of flavor.
  • Texture Balance: For a crunchy top, sprinkle some breadcrumbs mixed with a bit of butter over the mac and cheese before baking.
  • Fresh Herbs: Adding a sprinkle of chopped parsley or chives on top before serving can add a fresh pop of color and flavor.
  • Make Ahead: You can prepare the meatloaf mixture and mac and cheese separately, refrigerate them, and assemble right before baking.

These little tricks can elevate your dish, making it not only tasty but also a feast for the eyes. My grandmother always said that food should look as good as it tastes, and I couldn’t agree more.

Serving Suggestions and Pairings

Final dish - Ultimate Comfort: Mac and Cheese Meatloaf Casserole Magic

This casserole is quite filling on its own, but if you’re looking to round out the meal, consider serving it with a fresh garden salad or some roasted vegetables. A side of steamed broccoli or green beans can add a lovely contrast to the richness of the casserole. For a beverage pairing, a crisp white wine or a light beer complements the dish beautifully, enhancing the flavors without overpowering them.

Storage and Reheating Tips

Leftovers can be a blessing, especially when it comes to this casserole. Store any remaining portions in an airtight container in the refrigerator for up to three days. To reheat, cover the dish with foil and bake in a 350°F oven until heated through, about 20 minutes. Alternatively, you can microwave individual portions, though the oven method helps retain the dish’s texture better.

My husband Marco often looks forward to these leftovers as much as the main event, claiming they taste even better the next day!

Frequently Asked Questions

What are the main ingredients for Mac and Cheese Meatloaf Casserole?

The main ingredients for Mac and Cheese Meatloaf Casserole include the items listed in our ingredients section above. Each ingredient plays a crucial role in achieving the perfect flavor and texture.

How long does it take to make Mac and Cheese Meatloaf Casserole?

The total time to make Mac and Cheese Meatloaf Casserole includes both preparation and cooking time. Check the recipe card above for exact timing details.

Can I make Mac and Cheese Meatloaf Casserole ahead of time?

Yes, Mac and Cheese Meatloaf Casserole can often be prepared in advance. Store it properly in an airtight container in the refrigerator and consume within the recommended timeframe.

What can I serve with Mac and Cheese Meatloaf Casserole?

Mac and Cheese Meatloaf Casserole pairs well with various sides and accompaniments. Consider the serving suggestions mentioned in the recipe for the best dining experience.

Is Mac and Cheese Meatloaf Casserole suitable for special diets?

Depending on the ingredients used, Mac and Cheese Meatloaf Casserole may be adapted for various dietary needs. Check the ingredients list and consider substitutions as needed for your dietary requirements.

Final Thoughts

Mac and Cheese Meatloaf Casserole is more than just a recipe; it’s an invitation to savor the joy of cooking and the warmth of sharing a meal with loved ones. This dish brings together my love for simple, flavorful food and the cherished memories of cooking with my family. I hope it brings you the same joy and comfort it brings to my table. Remember, cooking is an act of creativity and care, something that nourishes not just the body, but the soul as well. Happy cooking, and may your kitchen be filled with the love and laughter that makes every meal memorable.

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